发育生物学研究中的模式动物

课程编码：0710I0D01005H 英文名称：Model Animals in Developmental Biology 课时：60 学分：4.00 课程属性：一级学科核心课 主讲教师：YUAN LI

The goal of this course is to introduce postgraduate students to the field of animal developmental biology, and to help them understand how the choice of model organisms matters for their research.

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第一章 Introduction to model animals in developmental biology 4学时 YUAN LI
第1节 What is developmental biology?
第2节 What are the model animals in developmental biology?
第二章 Studying developmental biology – tools and techniques 6学时 YUAN LI
第1节 Cell and molecular biology techniques
第2节 Developmental genetics
第3节 Experimental embryology
第三章 Introducing animal embryonic development 2学时 YUAN LI
第1节 The stages of animal development
第2节 Axis formation and Fate maps
第3节 Cell commitment
第四章 Cell-cell communication in development 5学时 YUAN LI
第1节 Cell adhesion and migration
第2节 Cell signaling
第3节 Epithelial-mesenchymal interaction and transition
第五章 Germ cells, fertilization and sex determination 5学时 YUAN LI
第1节 Primordial germ cells and Meiosis
第2节 Sex determination in mammals
第3节 Eggs and Sperm
第4节 Fertilization
第六章 Early Drosophila development and genes that pattern the Drosophila body plan 4学时 YUAN LI
第1节 Early development
第2节 Genes that pattern the Drosophila body plan
第七章 Early amphibian development 6学时 YUAN LI
第1节 Fertilization, cortical rotation, cleavage and Gastrulation
第2节 Progressive determination of the amphibian axes
第3节 Molecular mechanisms of amphibian axis formation
第4节 Specifying the left-right axis
第八章 Early zebrafish development 2学时 YUAN LI
第1节 Cleavage, Gastrulation and Axis formation
第2节 Introducing experimental methods
第九章 Early development in chickens 3学时 YUAN LI
第1节 Early development
第2节 Extraembryonic membranes
第十章 Early mammalian development 4学时 YUAN LI
第1节 Early development
第2节 Introducing mouse models of developmental disease
第十一章 Early development in C. elegans 3学时 YUAN LI
第1节 Normal development
第2节 Cell lineage
第十二章 Development of the nervous system 8学时 YUAN LI
第1节 The Emergence of the Ectoderm: central nervous system and epidermis
第2节 The neural crest cells and axonal specificity
第十三章 Organogenesis: 4学时 YUAN LI
第1节 Paraxial mesoderm: somitogenesis
第2节 Intermediate mesoderm: the urogenital system
第十四章 Repetition; Open-book examination 4学时 YUAN LI
第1节 examination

Prof. YUAN Li